Verzenio 200 mg/1

Verzenio Tablet is a product of Eli Lilly and Company

Group: Approved Kinase Inhibitor

Name: Verzenio

Dosage: Tablet

Strength: 200 mg/1

Route: Oral

Pharmaceutical company : Eli Lilly and Company

You can also find other alternative products such as : Verzenio (150 mg/1) from Eli Lilly and Company Verzenio (50 mg/1) from Eli Lilly and Company Verzenio (200 mg/1) from Eli Lilly and Company Verzenio (50 mg/1) from Eli Lilly and Company

Indication: Indicated in combination with fulvestrant for the treatment of women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer with disease progression following endocrine therapy. Inidicated as monotherapy for the treatment of adult patients with HR-positive, HER2-negative advanced or metastatic breast cancer with disease progression following endocrine therapy and prior chemotherapy in the metastatic setting.

Category:

  • Amines
  • BCRP/ABCG2 Inhibitors
  • BCRP/ABCG2 Substrates
  • Cytochrome P-450 CYP3A Substrates
  • Cytochrome P-450 CYP3A4 Substrates
  • Kinase Inhibitor
  • Kinase Inhibitors
  • MATE 1 Inhibitors
  • MATE 2 Inhibitors
  • MATE inhibitors
  • P-glycoprotein/ABCB1 Inhibitors
  • P-glycoprotein/ABCB1 Substrates
  • Pyridines
  • Food Interactions; Not Available

    Abemaciclib Definition:
    Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for the treatment of HR-positive and HER2-negative advanced or metastatic breast cancer that has progressed after unsuccessful endocrine therapy. It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with Fulvestrant. Following oral treatment in patients with HR-positive, HER2-negative breast cancer, abemaciclib demonstrated increased progression-free survival rates and objective response rates. Abemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor, and glioblastoma.

    More Verzenio 200 mg/1

    Verzenio

    Therapeutic indications This medication is used to treat certain types of breast cancer

    Before using this medication, if you have any of these conditions report them to your doctor or pharmacist..Nausea, vomiting, upset stomach, loss of appetite, weight loss, constipation, tiredness/weakness, headache, or change in how food tastes may occur.. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing..
    Abemaciclib may harm an unborn baby..**Precautions**Before taking abemaciclib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies..It is unknown if this drug passes into breast milk..


    VITAMIN And Minerals

    Therapeutic indications This medication is a multivitamin product used to treat or prevent vitamin deficiency due to poor diet, certain illnesses, or during pregnancy

    In the US -Call your doctor for medical advice about side effects..gov/medwatch..In Canada - Call your doctor for medical advice about side effects..
    **Interactions**Drug interactions may change how your medications work or increase your risk for serious side effects..If your brand of multivitamin also contains folic acid, be sure to tell your doctor or pharmacist if you take certain anti-seizure drugs (e..This medication may interfere with certain lab tests, possibly causing false test results..


    Mouthwash And Gargle

    Therapeutic indications Consult your pharmacist or physician

    fda.. You may report side effects to Health Canada at 1-866-234-2345..gov/medwatch..
    **Interactions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..


    C And Syrup

    Therapeutic indications This combination medication is used to treat symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (e

    Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur..In Canada - Call your doctor for medical advice about side effects..A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs..
    Talk to your pharmacist for more details..Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness.. This document does not contain all possible drug interactions..


    Johnson And Lotion

    Therapeutic indications This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e

    fda..Most emollients can be used safely and effectively with no side effects.. If any of these effects persist or worsen, tell your doctor or pharmacist promptly..
    **Interactions**If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them.. This product may contain inactive ingredients, which can cause allergic reactions or other problems.. Talk to your pharmacist for more details..


    C And E Capsule

    Therapeutic indications Consult your pharmacist or physician

    Consult your pharmacist or physician..List C And E Capsule side effects by likelihood and severity..gov/medwatch..
    **Precautions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..What should I know regarding pregnancy, nursing and administering C And E Capsule to children or the elderly?**Interactions**Consult your pharmacist or physician..


    Clear And Brite Drops

    Therapeutic indications Tetrahydrozoline is a decongestant used to relieve redness in the eyes caused by minor eye irritations (e

    List Clear And Brite Drops side effects by likelihood and severity..gov/medwatch..fda..
    Keep a list of all your medications with you, and share the list with your doctor and pharmacist..g..Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: MAO inhibitors (linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, isocarboxazid, tranylcypromine), guanethidine, tricyclic antidepressants (e..


    Hand And Body Lotion

    Therapeutic indications This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e

    If any of these effects persist or worsen, tell your doctor or pharmacist promptly.. You may report side effects to Health Canada at 1-866-234-2345..Most emollients can be used safely and effectively with no side effects..
    Talk to your pharmacist for more details..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..**Precautions**Before using this product, tell your doctor or pharmacist if you are allergic to any of the ingredients in the product; or if you have any other allergies..


    A And D Cream

    Therapeutic indications This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e

    .. If you notice other effects not listed above, contact your doctor or pharmacist..A very serious allergic reaction to this drug is rare..
    .. Some products may stain/discolor clothing.. Tell your doctor right away if you get sunburned or have skin blisters/redness..


    Allergy And Cold Elixir

    Therapeutic indications This combination medication is used to temporarily relieve symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis)

    Tell your doctor right away if any of these unlikely but serious side effects occur: mental/mood changes (such as confusion, hallucinations), ringing in the ears, difficulty urinating, vision changes (such as blurred/double vision)..Seek immediate medical attention if any of these rare but very serious side effects occur: fast/irregular heartbeat, seizure.. You may report side effects to Health Canada at 1-866-234-2345..
    Talk to your doctor if you are using marijuana.. Liquid products may also contain alcohol..This medication may interfere with certain medical/lab tests (such as brain scan for Parkinson's disease, urine drug screening tests), possibly causing false test results..


    Q And E Capsule

    Therapeutic indications Consult your pharmacist or physician

    List Q And E Capsule side effects by likelihood and severity..Consult your pharmacist or physician..
    Does Q And E Capsule interact with other medications?..**Precautions**Consult your pharmacist or physician..


    AA And C Tablet

    Therapeutic indications This medication is a combination of aspirin and caffeine

    You may report side effects to Health Canada at 1-866-234-2345.. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing..Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as nervousness, agitation), shaking (tremor), fast/pounding/irregular heartbeat, hearing changes (such as ringing in the ears, difficulty hearing), easy bleeding/bruising, unusual tiredness, signs of kidney problems (such as change in the amount of urine), nausea/vomiting that is severe or doesn't go away, yellowing eyes/skin, dark urine..
    Ask your pharmacist about using these products safely.. If you become pregnant or think you may be pregnant, tell your doctor right away..This drug contains aspirin..


    Aleve Sinus And Headache

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to FDA at 1-800-FDA-1088 or at www..fda..In Canada - Call your doctor for medical advice about side effects..
    **Precautions**Consult your pharmacist or physician..What should I know regarding pregnancy, nursing and administering Aleve Sinus And Headache to children or the elderly?**Interactions**Consult your pharmacist or physician..


    Gavilyte-H And Bisacodyl

    Therapeutic indications This medication is used to clean the intestine to prepare you for rectal or bowel examinations

    Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.. These effects are usually temporary.. You may report side effects to FDA at 1-800-FDA-1088 or at www..
    , dysphagia, history of aspiration).. This product may contain inactive ingredients, which can cause allergic reactions or other problems.. Consult your doctor before breast-feeding..


    Hair, Skin And NAILS

    Therapeutic indications Consult your pharmacist or physician

    In the US -Call your doctor for medical advice about side effects.. You may report side effects to Health Canada at 1-866-234-2345..
    **Precautions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..


    HAIR, SKIN AND NAILS

    Therapeutic indications Consult your pharmacist or physician

    List HAIR, SKIN AND NAILS side effects by likelihood and severity..In Canada - Call your doctor for medical advice about side effects..fda..
    Does HAIR, SKIN AND NAILS interact with other medications?Should I avoid certain foods while taking HAIR, SKIN AND NAILS?..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..**Precautions**Consult your pharmacist or physician..


    P And S Shampoo

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to Health Canada at 1-866-234-2345..In the US -Call your doctor for medical advice about side effects..fda..
    Keep a list of all your medications with you, and share the list with your doctor and pharmacist..**Precautions**Consult your pharmacist or physician..What should I know regarding pregnancy, nursing and administering P And S Shampoo to children or the elderly?**Interactions**Consult your pharmacist or physician..


    Pepsin And Rhubarb Granules

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to FDA at 1-800-FDA-1088 or at www..Consult your pharmacist or physician..fda..
    **Interactions**Consult your pharmacist or physician..**Precautions**Consult your pharmacist or physician..


    R And C Shampoo

    Therapeutic indications This medication is used to treat lice, which are tiny insects that can infest and irritate the scalp (head lice), the pubic area (crabs), or the body

    List R And C Shampoo side effects by likelihood and severity..This is not a complete list of possible side effects..fda..
    Keep a list of all your medications with you, and share the list with your doctor and pharmacist..During pregnancy, this medication should be used only when clearly needed.. Consult your doctor before breast-feeding..


    Aleve Cold And Sinus

    Therapeutic indications Consult your pharmacist or physician

    fda..Consult your pharmacist or physician.. You may report side effects to Health Canada at 1-866-234-2345..
    What should I know regarding pregnancy, nursing and administering Aleve Cold And Sinus to children or the elderly?**Interactions**Consult your pharmacist or physician..**Precautions**Consult your pharmacist or physician..


    Antiseptic And Anesthetic Liquid

    Therapeutic indications Consult your pharmacist or physician

    ..In the US -Call your doctor for medical advice about side effects.. You may report side effects to FDA at 1-800-FDA-1088 or at www..
    Does Antiseptic And Anesthetic Liquid interact with other medications?..**Precautions**Consult your pharmacist or physician..


    Kaminos And Minerals Capsule

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to Health Canada at 1-866-234-2345.. You may report side effects to FDA at 1-800-FDA-1088 or at www..
    ..**Precautions**Consult your pharmacist or physician..


    Head And Chest Solution

    Therapeutic indications Consult your pharmacist or physician

    gov/medwatch..In Canada - Call your doctor for medical advice about side effects..Consult your pharmacist or physician..
    What should I know regarding pregnancy, nursing and administering Head And Chest Solution to children or the elderly?**Interactions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..**Precautions**Consult your pharmacist or physician..


    J And Cream Protectant

    Therapeutic indications This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e

    Most emollients can be used safely and effectively with no side effects..Tell your doctor right away if any of these unlikely but serious side effects occur: unusual changes in the skin (e.. If you notice other effects not listed above, contact your doctor or pharmacist..
    **Precautions**Before using this product, tell your doctor or pharmacist if you are allergic to any of the ingredients in the product; or if you have any other allergies..g.. Ask your doctor or pharmacist for more details..


    PEG-3350 AND ELECTROLYTES

    Therapeutic indications PEG (polyethylene glycol) with electrolyte is used to clean out the intestines before certain bowel exam procedures such as colonoscopy or barium enema X-rays

    If any of these effects persist or worsen, tell your doctor or pharmacist promptly.. You may report side effects to FDA at 1-800-FDA-1088 or at www..A very serious allergic reaction to this drug is rare..
    Talk to your pharmacist for more details.. Consult your doctor before breast-feeding.. Room temperature solution is better for infants..


    R And C Kit

    Therapeutic indications This medication is used to treat lice, which are tiny insects that can infest and irritate the scalp (head lice), the pubic area (crabs), or the body

    gov/medwatch..A very serious allergic reaction to this drug is rare..This is not a complete list of possible side effects..
    What should I know regarding pregnancy, nursing and administering R And C Kit to children or the elderly?**Interactions**If your doctor has directed you to use this product, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them..Before using this medication, tell your doctor or pharmacist your medical history, especially of: skin infections..During pregnancy, this medication should be used only when clearly needed..


    Sinus And Cold-D

    Therapeutic indications Consult your pharmacist or physician

    In Canada - Call your doctor for medical advice about side effects..gov/medwatch..
    Keep a list of all your medications with you, and share the list with your doctor and pharmacist..What should I know regarding pregnancy, nursing and administering Sinus And Cold-D to children or the elderly?**Interactions**Consult your pharmacist or physician..


    VITAMIN A And D

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to FDA at 1-800-FDA-1088 or at www..In Canada - Call your doctor for medical advice about side effects..fda..
    **Interactions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..


    B And C Capsule

    Therapeutic indications This medication is a multivitamin product used to treat or prevent vitamin deficiency due to poor diet, certain illnesses, or during pregnancy

    If any of these effects persist or worsen, contact your doctor or pharmacist promptly..gov/medwatch..In the US -Call your doctor for medical advice about side effects..
    Before taking this medication, tell your doctor or pharmacist your medical history, especially of: use/abuse of alcohol, liver problems, stomach/intestinal problems (e.. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.. Do not start, stop, or change the dosage of any medicines without your doctor's approval..


    Bath And Shower Powder

    Therapeutic indications Consult your pharmacist or physician

    You may report side effects to FDA at 1-800-FDA-1088 or at www.. You may report side effects to Health Canada at 1-866-234-2345..fda..
    **Interactions**Consult your pharmacist or physician..Keep a list of all your medications with you, and share the list with your doctor and pharmacist..


    Effects of Verzenio 200 mg/1 by reaction with another drug or drugs

  • The metabolism of Abemaciclib can be decreased when combined with Mexiletine.
  • The metabolism of Abemaciclib can be decreased when combined with Acetazolamide.
  • The metabolism of Pethidine can be decreased when combined with Abemaciclib.
  • The serum concentration of Topiramate can be increased when it is combined with Abemaciclib.
  • The metabolism of Abemaciclib can be decreased when combined with Zafirlukast.
  • The metabolism of Abemaciclib can be decreased when combined with Sufentanil.
  • The serum concentration of Abemaciclib can be increased when it is combined with Palbociclib.
  • The serum concentration of Abemaciclib can be increased when it is combined with Yohimbine.
  • The metabolism of Simvastatin can be decreased when combined with Abemaciclib.
  • The metabolism of Abemaciclib can be increased when combined with Primidone.
  • Abemaciclib may decrease the excretion rate of Teniposide which could result in a higher serum level.
  • The serum concentration of Abemaciclib can be decreased when it is combined with Midostaurin.
  • The serum concentration of Clopidogrel can be increased when it is combined with Abemaciclib.
  • The serum concentration of Mitomycin can be increased when it is combined with Abemaciclib.
  • The metabolism of Abemaciclib can be increased when combined with Nevirapine.
  • Erlotinib may decrease the excretion rate of Abemaciclib which could result in a higher serum level.
  • Abemaciclib may decrease the excretion rate of Fluorouracil which could result in a higher serum level.
  • Abemaciclib may decrease the excretion rate of Testosterone which could result in a higher serum level.
  • The serum concentration of Hydrocortisone can be increased when it is combined with Abemaciclib.
  • The metabolism of Rivastigmine can be decreased when combined with Abemaciclib.