Acetadote 200 mg/1mL

Acetadote Injection, solution is a product of Cumberland Pharmaceuticals

Group: Approved Antidote for Acetaminophen Overdose / Antidotes / Cysteine / Expectorants / Free Radical Scavengers

Name: Acetadote

Dosage: Injection, solution

Strength: 200 mg/1mL

Route: Intravenous

Pharmaceutical company : Cumberland Pharmaceuticals

You can also find other alternative products such as : Cetylev (2.5 g/1) from Arbor Pharmaceuticals Acetadote (200 mg/1mL) from Cumberland Pharmaceuticals Cetylev (500 mg/1) from Arbor Pharmaceuticals Mucomyst (200 mg) from Well Spring Pharmaceutical Corporation Mucomyst (100 mg/1mL) from Bristol Myers Squibb Cetylev (2.5 g/1) from Arbor Pharmaceuticals Acetylcysteine Solution USP (200 mg) from Teligent Ou Cetylev (2.5 g/1) from Arbor Pharmaceuticals Acetylcysteine Solution (200 mg) from Sandoz Canada Incorporated Acetylcysteine Injection 200 mg/ml (200 mg) from Alveda Pharmaceuticals Inc Acetylcysteine Injection 200 mg/ml (200 mg) from Alveda Pharmaceuticals Inc Acetylcysteine (200 mg/1mL) from Paddock Laboratories, Inc. Acetadote (200 mg/1mL) from Cumberland Pharmaceuticals Acetadote (200 mg/1mL) from Cumberland Pharmaceuticals Acetadote (200 mg/1mL) from Cumberland Pharmaceuticals

Indication: Acetylcysteine is used mainly as a mucolytic and in the management of paracetamol (acetaminophen) overdose.

Category:

  • Amino Acids
  • Amino Acids, Neutral
  • Amino Acids, Peptides, and Proteins
  • Amino Acids, Sulfur
  • Anti-Infective Agents
  • Antidote for Acetaminophen Overdose
  • Antidotes
  • Antioxidants
  • Cough and Cold Preparations
  • Cysteine
  • Decreased Respiratory Secretion Viscosity
  • Expectorants
  • Free Radical Scavengers
  • Increased Glutathione Concentration
  • OATP1B1/SLCO1B1 Inhibitors
  • Ophthalmologicals
  • Protective Agents
  • Reduction Activity
  • Respiratory System Agents
  • Sensory Organs
  • Sulfhydryl Compounds
  • Sulfur Compounds
  • Food Interactions; Not Available

    Acetylcysteine Definition:
    Acetylcysteine (also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC) is primarily used as a mucolytic agent and in the management of acetaminophen poisoning. It is a derivative of cysteine with an acetyl group attached to the amino group of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase 1) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores. Acetylcysteine can also be used as a general antioxidant which can help mitigate symptoms for a variety of diseases exacerbated by reactive oxygen species (ROS). For instance, acetylcysteine is commonly used in individuals with renal impairment to prevent the precipitation of acute renal failure. Acetylcysteine has been shown to have efficacy in treating mild to moderate traumatic brain injury including ischemic brain injury, particularly in reducing neuronal losses, and also reducing cognitive and neurological symptoms when administered promptly after injury. N-acetylcysteine is now widely used in the treatment of HIV, and it has reported efficacy in chronic obstructive pulmonary disease and contrast-induced nephropathy. Acetylcysteine is also being successfully used to treat a variety of neuropsychiatric and neurodegenerative disorders including cocaine, cannabis, and smoking addictions, Alzheimer's and Parkinson's diseases, autism, compulsive and grooming disorders, schizophrenia, depression, and bipolar disorder. Recent data also shows that N-acetylcysteine inhibits muscle fatigue and can be used to enhance performance in endurance events and in exercise and endurance training. Acetylcysteine is also undergoing clinical trials as RK-0202, an oral rinse for the prevention and treatment of mucositis. It is comprised of acetylcysteine in a polymer matrix.

    More Acetadote 200 mg/1mL

    Acetadote Vial

    Therapeutic indications Consult your pharmacist or physician

    In Canada - Call your doctor for medical advice about side effects..Consult your pharmacist or physician..
    Keep a list of all your medications with you, and share the list with your doctor and pharmacist..**Precautions**Consult your pharmacist or physician..What should I know regarding pregnancy, nursing and administering Acetadote Vial to children or the elderly?**Interactions**Consult your pharmacist or physician..


    ACETADOTE Rx

    Therapeutic indications Poisoning/overdose


    >100kg: loading dose: 15,000mg over 1 hour; first maintenance dose: 5,000mg over 4 hours; second maintenance dose: 10,000mg over 16 hours.. Monitor for severe hypersensitivity reactions; may treat with antihistamines and epinephrine; interrupt or discontinue treatment if persistent.. Avoid fluid overload esp..


    ACETADOTE Rx

    Therapeutic indications Poisoning/overdose


    300mg/kg given as 3 separate doses and administered over a total of 21 hours.. Avoid fluid overload esp.. Warnings/Precautions: Asthma..


    Other drugs that have exactly the same effects, dosage, intended use, side effects, route of administration, risks, safety, and strength as Acetylcysteine

    Name Pharmaceutical
    Acetylcysteine 100 mg/1mLWest-Ward Pharmaceuticals Corp.
    Acetylcysteine 200 mg/1mLFresenius Kabi
    Acetylcysteine 6 g/30mLAuro Medics Pharma Llc
    Acetylcysteine 100 mg/1mLHospira Worldwide, Inc.
    Acetylcysteine 100 mg/1mLHospira Worldwide, Inc.
    Acetylcysteine 100 mg/1mLAmerican Regent
    Acetylcysteine 100 mg/1mLCardinal Health
    Acetylcysteine 100 mg/1mLAmerican Regent
    Acetylcysteine 100 mg/1mLWest-Ward Pharmaceuticals Corp.
    Acetylcysteine 200 mg/1mLHospira Worldwide, Inc.

    Over-the-counter(OTC) drugs

    Name Pharmaceutical
    Parvolex Liq IV 200mg/ml 200 mgBioniche Pharma (Canada) Ltd

    Effects of Acetadote 200 mg/1mL by reaction with another drug or drugs

  • The excretion of Mycophenolate mofetil can be decreased when combined with Acetylcysteine.
  • The excretion of Benzylpenicillin can be decreased when combined with Acetylcysteine.
  • The excretion of Olmesartan can be decreased when combined with Acetylcysteine.
  • The excretion of Repaglinide can be decreased when combined with Acetylcysteine.
  • The excretion of Repaglinide can be decreased when combined with Acetylcysteine.
  • The excretion of Olmesartan can be decreased when combined with Acetylcysteine.
  • The excretion of Lovastatin can be decreased when combined with Acetylcysteine.
  • The excretion of Olmesartan can be decreased when combined with Acetylcysteine.
  • The excretion of Methotrexate can be decreased when combined with Acetylcysteine.
  • The excretion of Liothyronine can be decreased when combined with Acetylcysteine.
  • The excretion of Lovastatin can be decreased when combined with Acetylcysteine.
  • The excretion of Ezetimibe can be decreased when combined with Acetylcysteine.
  • The excretion of Bosentan can be decreased when combined with Acetylcysteine.
  • The excretion of Dinoprostone can be decreased when combined with Acetylcysteine.
  • The excretion of Dinoprostone can be decreased when combined with Acetylcysteine.
  • The excretion of Caspofungin can be decreased when combined with Acetylcysteine.
  • The excretion of Bosentan can be decreased when combined with Acetylcysteine.
  • The excretion of Conjugated estrogens can be decreased when combined with Acetylcysteine.
  • The excretion of Bosentan can be decreased when combined with Acetylcysteine.
  • The excretion of Bosentan can be decreased when combined with Acetylcysteine.